The GSO framework is updated by testing its criteria on GRI case studies. The GSO publishes the case studies and carries out soft monitoring of how the criteria can be applied in different environments and through a RI lifecycle. This information helps in refining and updating the criteria.
The table below offers a list of the case studies carried out by the GSO.
| Name of the Laboratory | Year(s) of the discussion | Type | Lifecycle stage at the time of discussion |
| UG GRI – Underground Laboratories Global Research Infrastructure | 2015-2017 (GSO9) | National, distributed (LNGS in Italy, SNOLAB in Canada + dialogue with others) | Operation |
| IMPC GRI – International Mouse Phenotyping Consortium Global Research Infrastructures | 2015-2017 (GSO9) | International, distributed | Operation |
| ESS – European Spallation Source | 2015-2017 | International (ERIC), single-sited | Implementation |
| CHARS – Canadian High Arctic Research Station | 2015-2017 | National, single-sited | Design & Implementation |
| HAWC – High Altitude Water Cherenkov Observatory – HAWC | 2015-2017 | Bilateral, single-sited | Operation |
| Nuclotron-based Ion Collider fAсility – NICA | 2017 | International (JINR), single-sited | Implementation |
| Super Charm-Tau Factory – SCT | 2017 | National, single-sited | Design |
| MagLab – The National High Magnetic Field Laboratory | 2018 | National, single-sited | Operation |
| LBNF/DUNE – Long-Baseline Neutrino Facility/Deep Underground Neutrino Experiment | 2018 (GSO11) | International, dual-sited | Design and implementation |
| NEON – National Ecological Observatory Network | 2018 (GSO11) | National, distributed | Operation |
| EAST – Experimental Advanced Superconducting Tokamak | 2019 (GSO14) | National, single-sited | Operation |
| Chinese Ecosystem Research Network & GERI | 2019 (GSO14) | National, distributed. Linked to international collaboration | Operation |
| The Jinping Underground Laboratory | 2019 (GSO14) | National, single-sited | Operation |
| The High Energy Accelerator Research Organization (KEK) Tsukuba Campus | 2023 (GSO15) | National, single-sited | Operation |
| The High Energy Accelerator Research Organization (KEK) Tokai Campus | 2023 (GSO15) | National, single-sited | Operation |